Ideal for warmer months, the V-neck romper has a lightweight, airy feel thanks to its polyester and cotton blend material. The romper also has a relaxed fit that Amazon shoppers appreciate, adding to its breathability. The thin sleeves provide a bit of coverage that won't make you sweat, so you'll feel cool, calm, and collected even when it's 75 degrees out.
While the ruffled romper is definitely comfortable, reviewers are in love with its stylish design details as well. It has a deep V-neck cut that puts tasteful cleavage front and center and makes shoppers "feel so confident." The romper also has a tie feature that accentuates the waist, provides a flattering shape, and "hides the tummy," according to shoppers.
"This piece was an absolute show-stopper! [I] received compliments all day from friends and strangers, and I absolutely loved it," writes one Amazon shopper. "Very airy and flowy — perfect for summer."
"The fit was PERFECT! I'm 5'8 and ordered a size large, and thankfully everything about this jumpsuit was a match made in heaven!" writes another. "I often struggle to find a jumpsuit that nicely fits my tall frame, but thankfully this one fit in all the right places."
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MicroRNA Reverse Transcription Market Trends 2021 | Top Leaders, Competitive Landscape, and
MicroRNAs are highly conserved, small, single-stranded, non-coding RNA molecules that are involved in the regulation of gene expression. These molecules are transcribed by RNA polymerases II and III, that generate precursors which undergo cleavage to form mature microRNA.
– Highlights key business priorities in order to guide the companies to reform their business strategies and establish themselves in the wide geography
– Develop/modify business expansion plans by using substantial growth offering developed and emerging markets.
– Scrutinize in-depth global market trends and outlook coupled with the factors driving the market, as well as those restraining the growth at a certain extent.
– Enhance the decision-making process by understanding the strategies that underpin commercial interest with respect to products, segmentation and industry verticals.
About Us:
The Insight Partners is a one stop industry research provider of actionable intelligence. We help our clients in getting solutions to their research requirements through our syndicated and consulting research services. We are a specialist in Technology, Healthcare, Manufacturing, Automotive and Defense.
Chrissy Teigen poses for sweet family snap with husband John Legend and their two children |
And Chrissy Teigen was beaming from ear to ear as she posed for a sweet family snap with husband John Legend and their two children on Wednesday.
The model, 35, slipped into a white bikini as she headed out on a boat with the singer, 44, their daughter Luna, four, and their son Miles, two.
Chrissy opted for a classic white bikini as she and John sailed across the ocean during their island break.
The media personality sported a fun cardboard crown on her head in matching with her daughter as the family continued to enjoy their sunny break.
Clearly enjoying her vacation, Chrissy shared the snap to Instagram along with the caption: 'Yes day!'
Wow! It comes after the model looked nothing short of sensational as she posed in a pink swimsuit while enjoying the tropical waters on her lavish getaway
She cut a sizzling figure in the stylish one piece as she joked that it looked like she had photoshopped the image.
'I'm so upset': Paige Spiranac stunned by racism accusations as golf babe cops cancel culture for
The stunner took to Twitter on Sunday after Matsuyama clinched the iconic green jacket at Augusta, telling the Japanese hero that his victory was "well-deserved".
Spiranac then offered a casual compliment towards the cuisine in Matsuyama's homeland, igniting a far-fetched race storm in response.
"The menu for the champions dinner is going to be absolute fire next year", said Spiranac, only to be immediately met by anger and finger-pointing.
Honestly it's disgusting how everything gets twisted. I made a comment about how amazing the menu will be next year because I love Japanese food. Most winners create menus to honor where they are from and I would expect Hideki to do the same.
Spiranac seemed shaken by the saga. "Honestly, it’s disgusting how everything gets twisted," she hit back. "I made a comment about how amazing the menu will be next year because I love Japanese food.
"I don’t care if someone calls me a sl*t but to be called a racist is uncalled [for]. I would never and I’m honestly so upset about this."
More rational readers were as confused as they were willing to defend the tee-loving titillator.
Congo: Sassou Nguesso wins another term but still faces two big threats | African Arguments
President Denis Sassou Nguesso has ruled the Republic of Congo for 36 years over two periods. Credit: Paul Kagame.
On 21 March, the Republic of Congo held elections in which relatively few citizens bothered to participate, a fact that even President Denis Sassou Nguesso's campaign conceded. These were the third polls since the 77-year-old reclaimed power in the 1997 civil war and he won again with a decisive 88.57% .
Months before those polls, Sassou Nguesso organised a constitutional referendum that promised to remove term limits, give him immunity from domestic prosecution, and forbid his extradition to the International Criminal Court. Congolese citizens were outraged . Tens of thousands took to the streets in the largest protest movement for decades. Diaspora activists returned to the capital Brazzaville. Former allies denounced the "constitutional coup" and joined the opposition. Nonetheless, Sassou Nguesso claimed victory in the October 2015 referendum and subsequent March 2016 elections.
The March election itself was carefully managed. Officially, it featured six opposition candidates. In reality, four are widely believed to have been puppets paid by Sassou Nguesso to compete, recognise his victory, and give the election a veneer of legitimacy. Congo’s largest opposition party, the Pan-African Union for Social Democracy (UPADS), chose to boycott the proceedings altogether.
One of the genuine opposition candidates was former finance minister Mathias Dzon, but it was the other that provided the greater threat. Guy Brice Parfait Kolélas, affectionately dubbed Pako by his supporters, is the son of Bernard Kolélas, an icon of the early-1990s pro-democracy movement. He inherited his father’s political party and ethnic Lari base. Ahead of the election, Kolélas was also endorsed by Serge Yhombi-Opango, the son of the former president in 1977-79 who was from the same area as Sassou Nguesso. This endorsement let Kolélas bridge the north-south cleavage that has animated Congolese politics since independence.
The opposition called on the Constitutional Court to nullify the election due to fraud and the fact that Article 70 of the 2015 Constitution requires an election be annulled if a candidate is incapacitated, as Kolélas was. Given that Sassou Nguesso appointed the court's judges, the petition stands little chance of success.
Sassou Nguesso has largely undermined the Congo's political opposition, but he does face two challenges.
The first regards his decade-long attempts to quietly transfer power to his son, Denis Christel. Having cut his teeth in the national oil company, Denis Christel was elected to the National Assembly in 2012 with 99.88%. However, he enjoys relatively little support from the security apparatus, is regarded by Congolese citizens and the international community as profoundly corrupt , and remains the subject of ongoing legal proceedings in France and the US .
President Sassou Nguesso first considered handing power to his son ahead of the 2016 elections. It was only when those attempts failed that he resorted to the constitutional amendments. According to a source in the ruling family, he intended to try again ahead of the 2021 elections, but this plan was thwarted by an attempted palace coup in March 2020. This is what reportedly led Sassou Nguesso to impose a nightly curfew and close Congo’s borders, rather than – or at least as well as – the threat of COVID-19.
Allogene Therapeutics and SpringWorks Therapeutics Announce Dosing of First Patient in Phase 1
"We are pleased to have initiated this portion of the UNIVERSAL trial and look forward to investigating ALLO-715 in combination with nirogacestat as part of our comprehensive anti-BCMA strategy aimed at bringing an off-the-shelf cell therapy to patients with relapsed or refractory multiple myeloma," said David Chang, M.D., Ph.D., President, CEO and Co-Founder of Allogene Therapeutics.
Gamma secretase inhibition prevents the cleavage and shedding of BCMA from the surface of multiple myeloma cells. In preclinical models, nirogacestat has been shown to increase the cell surface density of BCMA and reduce levels of soluble BCMA, which may enhance the activity of BCMA-targeted therapies. 1 In addition, emerging clinical data suggest that a GSI may increase antitumor efficacy of BCMA-targeted autologous CAR T therapy in patients with relapsed and refractory multiple myeloma. 2, 3
The Phase 1 trial ( NCT04093596 ), which is part of the ongoing UNIVERSAL trial being conducted by Allogene, is an open-label study evaluating the safety, tolerability and preliminary efficacy of ALLO-715 in combination with nirogacestat in patients with relapsed or refractory multiple myeloma. The trial is being advanced pursuant to a clinical trial collaboration agreement between Allogene and SpringWorks. Under the terms of the agreement, Allogene is sponsoring and conducting the Phase 1 study. Allogene and SpringWorks have formed a joint development committee to oversee this portion of the clinical study.
ALLO-715 utilizes the TALEN® gene-editing technology pioneered and owned by Cellectis. Allogene has an exclusive license to the Cellectis technology for allogeneic products directed at the BCMA target. Allogene holds the global development and commercial rights for this investigational candidate.
About Nirogacestat
Nirogacestat is an investigational, oral, selective, small molecule gamma secretase inhibitor in Phase 3 clinical development for desmoid tumors, which are rare and often debilitating and disfiguring soft-tissue tumors. Gamma secretase cleaves multiple transmembrane protein complexes, including Notch, which is believed to play a role in activating pathways that contribute to desmoid tumor growth.
Allogene Media/Investor Contact:
Christine Cassiano
Chief Communications Officer
(714) 552-0326
Christine.Cassiano@allogene.com
SpringWorks Media/Investor Contact:
Kim Diamond
Vice President, Communications and Investor Relations
203-561-1646
kdiamond@springworkstx.com
2 Cowan et al., Abstract #204 "Efficacy and Safety of Fully Human BCMA CAR T Cells in Combination with a Gamma Secretase Inhibitor to Increase Bcma Surface Expression in Patients with Relapsed or Refractory Multiple Myeloma", ASH 2019.
4 Multiple myeloma - Genetics Home Reference - NIH. Retrieved from https://ghr.nlm.nih.gov/condition/multiple-myeloma#
Best sports bra for big bust support in 2021 | The Independent
Boobs are beautiful: fact. All shapes and sizes, big, small, perky or not – they're fab. But, when you're a woman who is blessed with slightly larger assets, shopping for underwear is no easy task.
In the past, the bras that would range beyond a double-D were the most basic you could find. They'd usually come in the standard three tones – black, white and nude – and they'd tend not to have any frills.
That might not seem important, but we all know that when you've got underwear on that looks good, regardless of whether anyone is seeing it, it gives you an all-important confidence boost.
We're pleased to say, however, that things have started to improve. Brands like Savage X Fenty are paving the way with a host of bras that are stylish and sexy without compromising on support. But when it comes to finding an equally stylish and supportive sports bra, the perfect model can still prove elusive.
We know the pain of relying on a standard bra – which, let's face it, was not made for jumping jacks and burpees. So, we made it our mission to find some decent options for the larger breasted woman among us, so you too can have peace of mind throughout even the most arduous workout.
There were three main things we were looking for in our sports bras. Firstly, they had to be comfortable – we didn't want wires digging into our ribcage or straps leaving those dreaded red marks on our shoulders.
They also had to be flexible, with our ideal bra having adjustment options and being able to handle an intense HIIT class as well as a gentler yoga or stretch session. Most importantly, though, they had to be supportive.
You can trust our independent reviews. We may earn commission from some of the retailers, but we never allow this to influence selections, which are formed from real-world testing and expert advice. This revenue helps to fund journalism across The Independent.
Panache's wired sports bra has been a firm favourite for us for some time now. We've worn it for every kind of activity – high-intensity workouts, dancing, yoga and even just running errands – and without fail, it always holds up (pun intended). It's not only fashion forward, but comfortable and super supportive. The underwire is strong and thick, but as it's concealed under thick gel padding, you barely even notice it's there. Similarly, the cups are moulded, encapsulating each breast and giving great coverage, control and a defined shape. Plus, as it's seam-free, it feels smooth and soft against the skin, which is a welcome comfort.
Bhad Bhabie: Subscribe to all these stars with an Onlyfans account – Film Daily
Celebrities have decided to join in by creating OnlyFans accounts to capitalize on their popularity and cash out on the trending opportunity. Here are a few celebs you can check out on OnlyFans now!
Sex workers across the board were upset by the whole ordeal because Bella Thorne's choice to infiltrate into the world of OnlyFans forced the site to change some of its rules & regulations. Non-famous content creators running OnlyFans accounts started to see their income deplete after Bella Thorne joined the platform.
Jordyn Woods consulted with several sex workers before signing on to make sure that she wasn't stepping on anyone's toes. She has also been using the site to show the world she's proud of embracing her natural body & authentic self.
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