CONCLUSIONS: The proposed protocol allows a specific and sensitive confirmation of SARS-CoV-2 infections close to the detection limits of RT-qPCR. The tested biotinylated primers do not negatively affect the RT-qPCR pipeline and thus can be optionally applied to enable deeper inspection of RT-qPCR results by subsequent pyrosequencing. Moreover, due to the incremental transmission of SARS-CoV-2 variants of concern, we note that the used strategy can uncover (Spike) P681H allowing the pre-selection of SARS-CoV-2 B.1.1.7 candidate specimens for deep sequencing.
Oscars 2021: Elizabeth Hurley looks wears plunging gold dress for Elton John's VIRTUAL party |
And Elizabeth Hurley ensured to still put on a glamorous display as she got ready to attend Elton John's 'legendary' Oscars party from home on Sunday night.
The actress, 55, flaunted her ample cleavage in a plunging gold dress which was adorned with sequins for the virtual showbiz event.
Elizabeth looked sensational in a short clip shared to Instagram, shot as she posed behind her bar and cradled a drink ahead of the star-studded event kicking off.
The brunette beauty wore her long locks down and perfectly styled into loose curls, letting her glossy tresses cascade over her shoulders.
She ensured all eyes were on her show-stopping gown and phenomenal figure by going without any jewellery.
Always one to look her best, Elizabeth completed her Oscars party look by rocking a full face of makeup including a slick of eyeliner and pink lipstick.
Stunning: The actress, 55, flaunted her ample cleavage in a plunging gold dress as she shared a short clip encouraging others to join her at the virtual event to Instagram
Get involved! Elizabeth told fans they could also take part in the infamous showbiz event, which will see Neil Patrick Harris hosting and Dua Lipa performing, for just £14.99
Halle Berry Goes Full Glam in Gorgeous Oscars 2021 Dress | PEOPLE.com
Halle Berry, a presenter this year, brought her high-fashion A-game (and a brand-new do) to the red carpet at the 93rd annual Academy Awards
Halle Berry has been pulling off red carpet-level looks in her own backyard . So it's no surprise the multi-hyphenate star delivered a serious style flex for her return to the Academy Awards on Sunday night.
Berry donned a flowy mauve-toned strapless gown with a plunging sweetheart neckline and a large bow attached to the bodice. But it was her glam that really stole the show: The star debuted a blunt bob and baby bangs.
Berry last presented at the Oscars in 2017 , with another truly show-stopping style moment. She wore a sheer, sparkling, one-shoulder Atelier Versace gown, but the cornerstone of her look was her natural curls . (In fact, Google searches for her name spiked 1,350 percent that year.)
The actress told Vogue at time, "The dress is glamorous with a sense of romance that made me feel feminine and fresh. With this look, I celebrate my natural hair by allowing it to be wild and free."
For many, the star's most memorable look is likely the Elie Saab gown she wore to the 2002 Academy Awards. Berry arrived in the sweeping burgundy design featuring a sheer bodice with floral embroidery.
While dress was a jaw-dropper (and arguably put designer Saab on the map), even more exciting was her historical win that night. Berry took home the Best Actress statue for her role in Monster's Ball — and making history as the first ever Black woman to win a Best Actress in a Leading Role Oscar category.
RELATED: Halle Berry Bares Her Abs in a Crop Top and Ball Skirt Just Because: 'Looking for a Red Carpet'
Need more of a Berry fashion fix? Take a look back at the red carpet vet's Oscars style evolution below.
Oscars 2021: Mank star and nominee Amanda Seyfried wears red ballgown on pink carpet | Daily Mail
The 35-year-old actress, who is nominated for Best Supporting Actress for her role in Best Picture nominee Mank, stunned in a scarlet gown as she arrived at the 93rd Academy Awards on Sunday.
Seyfried opted for an Armani Privé dress in a fishtail silhouette with a plunging slit on the bodice, showing off a glimpse of cleavage.
The Mamma Mia! stunner wore her locks back in an elegant chignon and wore a deep shade of red on her lips.
In the Best Supporting Actress category, the actress is up against Borat Subsequent Moviefilm's Maria Bakalova, Olivia Colman in The Father, Glenn Close for Hillbilly Elegy, and You Yuh-Jung for Minari.
The Academy of Motion Picture Arts and Sciences is hosting the delayed ceremony at the historic Union Station in Los Angeles, California where socially distanced movie stars can go mask-free while on-camera or seated in the main show room.
During a year that saw movie theatres closed due to the pandemic, there were eight new films that did manage to impress Academy voters enough to be in contention for Hollywood's biggest award, the Oscar for Best Picture (last year there were nine nominees in the category.)
While blockbusters may be absent this year, there have been a wide range of movies that have caught the attention of Academy voters, including the lavish Mank, Netflix's ode to the Golden Age of Hollywood, starring Gary Oldman and Amanda Seyfried.
Oscars 2021: Nominee Tiara Thomas wears plunging white pantsuit and diamond lariat on red carpet
Tiara Thomas made a stunning statement in a Jovana Louis plunging pant suit as she arrived to the 93rd annual Academy Awards held at Union Station in Los Angeles .
The 31-year-old singer is nominated for Best Song at the coveted award ceremony for I Can't Breathe — which she cowrote with H.E.R. — and she looked ethereal in an eye-catching all white number.
The song's title is a nod to the late George Floyd as the ladies spoke about the song being a symbol of change and it's importance in the Black community.
And her plunging top showcased a hint of cleavage as she continued to draw attention to her décolletage with a diamond lariat necklace that featured a tropical flower fixed to it.
The Indiana native wore her hair tied back with braids lining her head and a few baby hairs were strategically curled to her forehead for soft balance.
Naturally she found herself at the top of the best dressed list as E! Red Carpet hosts Brad Goreski and Nina Parker marveled at her look.
Dually nominated: The singer is nominated for Best Song for 'I Can't Breathe,' and her song 'Fight For You' from Judas And The Black Messiah was nominated for Original Song for a Motion Picture
Oscars red carpet 2021: Marlee Matlin, 55, wears long black and silver gown for 93rd Academy
And Marlee Matlin, 55, radiated star power as she stepped onto the red carpet of the 93rd annual Academy Awards at Union Station in Los Angeles on Sunday.
The Coda talent, who made history as the only deaf actor to win an Oscar, dazzled in custom Vivienne Westwood gown made with sustainable fabric and decorated with an intricate botanical design in sequins.
Glowing: Marlee Matlin stunned in a custom black and silver Vivienne Westwood dress with dramatic sleeves during Sunday's Academy Awards ceremony at LA's Union Station
Matlin's dress - which was made of newly launched Red Carpet Green Dress black vegan textile made with TENCEL Luxe filaments incorporating an archival Westwood fabric - hung off her shoulders ever-so-slightly, showing off her collarbone and a hint of cleavage.
Swarovski crystal details adorned the sleeves of the look, which was part of Suzy Amis Cameron's Red Carpet Green Dress™ (RCGD) initiative, highlighting ethically and sustainably made awards season fashion.
The star - who presented during this year's event - placed one hand on her hip, letting the sheer, split sleeves of her frock sweep down as she flashed a giant sparkler which came with elegant drop earrings to match.
Her hair was styled to the side in soft waves, while she amped up the glamour with smoky eyes and a glossy, nude lip.
It seemed the beauty was excited for the show, sharing a snap of her tickets and some extra Oscar swag on Instagram right ahead of the show.
Oscars 2021: Isla Fisher and nominee Sacha Baron Cohen celebrate in Sydney | Daily Mail Online
The couple glammed up in the early hours of Monday morning (AEST) and posed for a selfie in front of Sydney's iconic Harbour.
Oscars, Sydney style! Isla Fisher and Sacha Baron Cohen attended a screening of the 93rd annual Academy Awards on Monday morning in Sydney, Australia
Dapper: Meanwhile, Borat star Sasha, 49, looked dapper in a chocolate tuxedo jacket and matching bow tie, a white shirt and cream trousers
The Wedding Crashers star, 45, showed off her cleavage in elegant low-cut black gown, which she accessorised with a stunning diamond choker necklace.
Her signature red hair was coiffed in loose waves and she added a pop of colour with some bright red lipstick.
Sign of the times: The awards show will be very different as it will be a socially distanced event held not in Hollywood but in downtown Los Angeles at Union Station with only 170 people and not the usual 3,000. Isla and Sasha are celebrating at a special screening in Sydney
Potential new COVID vaccine from Australia
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The development of new and storage-friendly vaccines would be beneficial for countries that have struggled to inoculate their populations.
The SARS-CoV-2 sclamp antigen vaccine was produced using hamster vary cells and uses the spike glycoprotein ectodomain fused to a molecular clamp. The recombinant protein uses the SARS-CoV-2 strain first detected in Wuhan, China, with several alterations, including replacing the furin cleavage site of spike glycoprotein amino acids and removing the C-terminal domain.
Prior work on the vaccine has shown it adopting a native prefusion conformation that would bind to ACE2 receptor and monoclonal antibodies specific to the virus. Unlike the currently available mRNA viruses, the Sclamp vaccine is refrigerated at 2 to 8°C.
The phase 1 clinical trial took place in Brisbane, Australia, from June 23, 2020, to August 17, 2020. The researchers screened 314 adults ranging from 18 up to 55 years of age for eligibility into the study. Eligibility included people who tested negative for SARS-CoV-2, had no prior exposure to someone with the virus, and showed no evidence of antibodies specific to SARS-CoV-2 that would indicate a previous infection.
About 120 participants met study criteria and were then randomly selected to one of five treatment groups that would include a placebo, two vaccine doses at different quantities (5 μg, 15 μg, or 45 μg) administered intramuscularly, or only one dose of the vaccine at 45 μg with placebo at the second dose. All participants were given their first dose on day 1 and the other dose on day 29 of the study. Of the original 120, 114 or 95% of participants completed the trial up to day 57.
The vaccine was well-tolerated overall, with a majority of vaccine-induced side-effects to be expected by researchers. The following gained expected adverse effects: 79% of participants in the placebo group, 92% in the 5 μg group, 96% in the 15 μg group, 83% participants in the single vaccine dose 45 μg group, and 88% in the two-dose 45 μg vaccine group.
Adverse events that would have been related to the vaccine happened in one participant in the placebo group, 17% in the 5 μg group, 13% in the 15 μg group, 17% participants in the single-dose 45 μg group, and 4% in the two-dose 45 μg vaccine group.
The most common expected side effect seven days after vaccination was mild or moderate pain and tenderness around the injection site. This was reported more in participants of any vaccine group compared to the placebo group.
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