Thursday, February 18, 2021

The origin of SARS-CoV-2 furin cleavage site remains a mystery

The SARS-CoV-2 is a betacoronavirus, and is most closely related to the bat SARS-related coronavirus (SARSr-CoV) represented by the genome sequence RaTG13, which shares 96% identity with the former. This has made the bat virus the most probable precursor of the virus in current circulation.

Furin acts on substrates with single or paired basic residues during the processing of proteins within cells. Such a polybasic furin cleavage site is found in various proteins from many viruses, including Betacoronavirus Embecoviruses, and the Merbecovirus. However, within the betacoronaviruses of the sarbecovirus lineage B, this type of site is unique to SARS-CoV-2.

Publisher: News-Medical.net
Date: 2021-02-17T08:57:00.0000000-05:00
Twitter: @NewsMedical
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Tarsha Whitmore Glistens In A Tiny White Bikini That Reveals Serious Cleavage - The Inquisitr

Australian bombshell Tarsha Whitmore stunned her 887,000 Instagram followers with her latest share, a steamy snap taken poolside. The photo was captured in Gold Coast , Queensland, Australia, as the geotag indicated,  and she perched her peachy posterior on the edge of a pool, with her feet resting on the first step in a series of shallow stairs covered by water.

Tarsha's bikini top was strapless, with two square-shaped cups bordered with ruffles along the cup and bottom. Thin straps extended across her chest, connecting the cups. The garment revealed a tantalizing amount of cleavage, with her sculpted shoulders and arms were on display as well. Ruched detailing across each cup accentuated her ample assets even more, highlighting her curvaceous figure.

Publisher: The Inquisitr
Date: 2021-02-18T18:52:48.000 00:00
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Phage-assisted evolution of botulinum neurotoxin proteases with reprogrammed specificity | Science

By Travis R. Blum , Hao Liu , Michael S. Packer , Xiaozhe Xiong , Pyung-Gang Lee , Sicai Zhang , Michelle Richter , George Minasov , Karla J. F. Satchell , Min Dong , David R. Liu

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A versatile platform reprograms botulinum neurotoxin proteases to selectively cleave proteins of biomedical interest in vitro and in neurons.

Publisher: Science
Date: 2021-02-19
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Anna Katharina Flaunts Ample Cleavage In Plunging Black Leather Top - The Inquisitr

The 28-year-old American bombshell was captured in front of a gray backdrop for the four-photo slideshow. She struck several attention-grabbing poses which highlighted her fit physique.

In the first slide, she stood facing the camera as she popped one hip out. She placed her left arm across her midriff and put her right thumb up to her mouth as she stared directly at the lens. The second snapshot captured her touching her pants and pursing her lips as she looked away from the camera's lens. In the third image, she placed one hand on her locks and the other on her thigh as she cocked one hip again.

Publisher: The Inquisitr
Date: 2021-02-15T10:12:22.000 00:00
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Erratum for the Report "CRISPR-Cas12a target binding unleashes indiscriminate single-stranded

In the Report " CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity " the following corrections have been made.

After publication, a data analysis error was brought to the authors' attention. The initial velocity ( V 0 ) plotted in Fig. 2D and fig. S7 was calculated incorrectly. The fluorescence intensity was used directly in the calculation of V 0 rather than being converted first to molar concentrations. As a result, there is a ~100-fold difference between the reported and the correct Michaelis-Menten values.

Publisher: Science
Date: 2021-02-19
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Kinsey Wolanski Flashes An Eyeful Of Cleavage In Plunging Top While Holding A Bear-Shaped Bouquet

Kinsey Wolanski added some serious heat to her social media feed with the most recent update that was featured on her Instagram page. The model shared two new shots on February 10, and they have been earning plenty of attention from her 3.7 million fans.

The smoking-hot share was her latest promotion for Dose of Roses, and she worked it for the camera. She chose an outdoor space as the location for her shoot. The model stood in front of a wood fence with overgrown greenery on the top. She faced the lens, tilting her head to the side and wearing a slight smile. Kinsey ran one hand through her silky blond tresses and held a bear-shaped bouquet of roses in the other. The adorable flower arrangement had a logo bow with a yellow gem in the middle.

Publisher: The Inquisitr
Date: 2021-02-11T13:52:46.000 00:00
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Susanna Reid 'loves' attention cleavage gets on GMB post 50th as Piers shares her

Speaking in a new interview, the 55-year-old said Susanna now thinks "f*** it" when it comes to stories on her appearance.

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It comes after the mother-of-three sparked frenzy on her GMB return after Christmas, as she debuted a new 'do and low-cut lacy dress.

"When she turned 50 something changed, because she was voted as having the best bottom in the world and couldn't be happier."

The star marked the milstone on December 10, with low-key celebrations with her family due to lockdown.

Publisher: Express.co.uk
Date: 2021-02-06T08:54:00 00:00
Author: Jessica Earnshaw
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20 Farfetch Sale Lingerie Pieces to Shop in 2021 | SELF

Farfetch has plenty of discounted pieces up for grabs for those seeking extra support for their cleavage or an opportunity to upgrade their underwear drawer. From designer brands like Calvin Klein and Dolce & Gabbana to smaller, cultier names like Ganni, the Farfetch sale is an excellent opportunity to round out your base layers . These lingerie pieces are going fast, as many items are down to their last few sizes, so take advantage of these markdowns before they're gone.

Publisher: SELF
Author: Tiffany Dodson
Twitter: @SELFmagazine
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