
Published in Alzheimer⁘s ⁘ Dementia: The Journal of the Alzheimer⁘s Association , the research sheds light on how everyday habits, like how much time we spend sitting, may play a powerful role in brain health as we age.
Researchers from Vanderbilt University Medical Center and the University of Pittsburgh analyzed more than 400 adults aged 50 and older.
Participants were asked to wear activity-tracking devices for ten consecutive days, providing detailed data on how much time they spent sitting or lying down. The researchers then analyzed this sedentary behavior against cognitive tests and brain imaging over a seven-year period.
Individuals who were more sedentary experienced greater cognitive decline and notable shrinkage in brain regions critical for memory and Alzheimer⁘s development.
In fact, the researchers said its sample of participants were quite active while wearing the devices, with 87% of participants meeting the CDC recommendation of at least 150 min of MVPA per week.⁘
The team said this provides ⁘strong evidence that even among a physically active cohort, such increased activity is not protective from the impact of greater sedentary behavior and brain health, especially among APOE-e4 carriers.⁘⁘
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