Friday, January 21, 2022

A compensatory link between cleavage/polyadenylation and mRNA turnover regulates steady-state mRNA

Publisher: PNAS
Author: Copyright 2022 the Author s Published by PNAS https creativecommons org licenses by nc nd 4 0 This article is distributed under Creative Commons Attribution NonCommercial NoDerivatives License 4 0 CC BY NC ND
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COVID-19: Studying variants' mutations overturns assumptions

However, a recent study from researchers at Cornell University, in Ithaca, NY, suggests that this mutation at the furin cleavage site did not influence Alpha's ability to spread between or infect cells.

Errors during the replication of the SARS-CoV-2 virus result in mutations in its genome. This produces variants.

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Date: 2022-01-20T15:02:00.000Z
Author: Deep Shukla
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Tilly Ramsay nearly flashes her cleavage in front of a giggling Maisie Smith during Strictly tour

Tilly Ramsay nearly flashed Maisie Smith with her cleavage in a hilarious dressing room video taken during the Strictly Come Dancing tour in Birmingham .

The influencer, 20, attempted to shimmy for the camera before gasping in shock after her red dressing gown flapped open in the Thursday Instagram clip.

Publisher: Mail Online
Date: 2022-01-21T10:37:06 0000
Author: Callum Wells
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Recurrent mutations in topoisomerase IIα cause a previously undescribed mutator phenotype in human
Publisher: PNAS
Author: Copyright 2022 the Author s Published by PNAS https creativecommons org licenses by nc nd 4 0 This article is distributed under Creative Commons Attribution NonCommercial NoDerivatives License 4 0 CC BY NC ND
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Researchers explore furin inhibitors as a potential tool for treating COVID-19 infection

Furin is a protease enzyme that helps inactive proteins move to a biologically active state. In viruses, furin can cleave sites that help to make the virus more infectious.

Furin is a transmembrane that helps cleave the spike protein, which has helped respiratory viruses such as the Middle East respiratory syndrome coronavirus (MERS-CoV) turn inactive proteins into active ones that promote infection.

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Publisher: News-Medical.net
Date: 2022-01-20T10:43:00.0000000-05:00
Twitter: @NewsMedical
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Sigma-Aldrich Files Substantive Preliminary Motion 1 to Change the Count in Interference No.

On November 19th, Senior Party Sigma-Aldrich filed its Substantive Preliminary Motion No. 1 in CRISPR Interference No. 106,132 (where the Broad Institute, Harvard University and MIT, collectively, "Broad" is the Junior Party) asking the Board to substitute the Count pursuant to 37 C.F.R.

In its Statement of Precise Relief Requested, Sigma-Aldrich sets forth its proposed Count 2 as, in the alternative, CVC Application No. 15/947,680, claim 164 or Sigma-Aldrich Application No.

Publisher: JD Supra
Twitter: @jdsupra
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Kirsty Gallacher turns heads in plunging jumpsuit as she rings in her 46th birthday with pals |

But Kirsty Gallacher shared no signs of heartache as she celebrated her 46th birthday at Langan's Brasserie in London on Thursday night.

The presenter wowed in a plunging black jumpsuit as she joined Natalie Pinkham, SJ Mee and Zoe Hardman for a night of celebrations.

Publisher: Mail Online
Date: 2022-01-21T12:31:38 0000
Author: Connie Rusk
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'Demon Slayer 2' lands in controversy; here's why netizens demand show to be 'cancelled'

The second season of Demon Slayer: Kimetsu no Yaiba is currently underway. The series has sparked massive interest from anime lovers in the world upon its release in October and has been entertaining fans since then. However, the show seems to have landed in a controversy.

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Publisher: Republic World
Date: 2022-01-21T11:29:00 05:30
Author: Republic World
Twitter: @republic
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The "LLQY" motif on SARS-CoV-2 spike protein affects S incorporation into virus
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Publisher: Docwire News
Twitter: @mydocwire
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Amber Rose dons clinging athleisure as she snuggles up with cheating baby daddy Alexander Edwards

Amber Rose was spotted while out to dinner date with on-again, off-again baby daddy, Alexander Edwards, and her family.

At one point, the pair were seen smoking cigarettes together outside the quaint Indian eatery, Flavor Of India , in the Studio City neighborhood of Los Angeles on Thursday.

Publisher: Mail Online
Date: 2022-01-21T08:24:55 0000
Author: Kevin Kayhart
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