In a study posted to the bioRxiv * pre-print server, a team of researchers analyzed the furin cleavage site (FCS) of the spike (S) protein of rodent coronavirus AcCoV-JC34 from the sub-genus luchacovirus, along with the other luchacoviruses, using in vitro and computational
QTQTN motif upstream of furin-cleavage site in SARS-CoV-2 infection and pathogenesis
Another novel amino acid motif – QTQTN, is found directly upstream of the FCS, which is also absent in other group 2B CoVs. This motif is often deleted and has been rampant in cultured virus stocks of the alpha, beta and delta variants.
A new study posted to the bioRxiv * preprint server aimed to demonstrate whether the loss of the QTQTN motif attenuates SARS-CoV-2 replication in respiratory cells in vitro and pathogenesis in hamsters.
Urfi Javed shows cleavage in cut-out pantsuit; fans ask these questions [VIDEO]
Urfi Javed who has been a part of Bigg Boss OTT makes headlines for her sartorial picks. She grabs the limelight because of her dressing sense, and today was one such similar occasion where she was questioned for her attire.
Urfi Javed who has been a part of Bigg Boss OTT, makes headlines for her attires. She grabs the limelight because of her dressing sense, and this time it was the same. A video clip of the actress surfaced online where she was criticised for the outfit that she had worn.
Alnylam Submits CTA Application for ALN-APP, an Investigational RNAi Therapeutic for the
The managers of the $1.2 billion Neuberger Berman Intrinsic Value fund will engage companies in proxy fights if they are poorly run, and take other steps to avoid value traps.
As the cannabis industry starts to develop and overcome major challenges, find out what's in store for 2022.
Dr. Alina Chan doubles down on COVID-19 origin theory
Dr. Alina Chan has seen her work called a “ farce ” by the New Republic and “goofy” by Texas A&M head of biology Benjamin Neuman . China’s government-run Global Times newspaper maintained that she had "filthy behavior and a lack of basic academic ethics.
"This is so controversial that masks and vaccines result in threats coming at scientists," she said at a Science and Technology Select Committee Q&A in London last week. "It's unavoidable. I'm not in a rare situation … There are potential career effects.”
Pic Talk: Mallu Beauty Malavika Mohanan's Cleavage Show
Malayali beauty Malavika Mohanan is one of the most glamorous actresses in South Indian cinema. While the actress hasn’t played a glamour doll role on screen yet, she has the knack of setting the digital screens on fire with her red-hot glamour show on social media.
Malavika’s stellar cleavage show is an instant attention-grabber. The Mallu beauty really is gifted with a shapely figure and she has no qualms when it comes to flaunting the same.
COVID-19: Omicron Variant Less Likely to Cause Serious Lung Illness Compared to Delta | The
The Omicron variant of COVID-19 may be significantly better than previous variants at evading vaccine-induced antibodies. Still, preliminary evidence also suggests that it is less likely to cause severe illness in the lungs compared to Delta.
In a yet-to-be peer-reviewed study, a team of researchers led by Indian-origin Professor Ravi Gupta from the University of Cambridge created synthetic viruses, known as 'pseudo viruses' that carried key mutations found in the Delta and Omicron strains to study the virus's behavior.
Nigeria's commodity terms of trade decline 2.8 % as exports fall 2.3%
Nigeria's all commodity terms of trade (ToT) fell by 2.85 percent in the third quarter of 2021 (Q3'21) even as commodity exports declined by 2.3 percent during the period.
This represents the third consecutive quarterly and highest decline in commodity ToT this year. In Q1'21 commodity ToT declined by 0.51 percent and by 0.35 percent in Q2'21.
Miss Manners: Someone took a video in my home without permission - The Washington Post
We were enjoying a fun evening with extended family: playing cards, drinking wine and ultimately turning up the music and showing off our best awkward dance moves. At this point, I noticed my son's girlfriend standing in the corner of the room taking a video with her phone.
Researchers Uncover a Brain Protein as Potential Autism Biomarker
Their findings are published in the journal Neuron in a paper titled, “ Shed CNTNAP2 ectodomain is detectable in CSF and regulates Ca2+ homeostasis and network synchrony via PMCA2/ATP2B2 .”
“Although many neuronal membrane proteins undergo proteolytic cleavage, little is known about the biological significance of neuronal ectodomain shedding (ES),” the researchers wrote.
Happening on Twitter
Our modest contribution to the debate around acquisition of furin cleavage site. Several reservoir-bound CoVs have… https://t.co/rlxudv2RD6 c_drosten (from Berlin, Germany) Thu Dec 16 11:27:32 +0000 2021
So, doesn't this put to rest the whole "SARS-CoV-2 had to have come out of the Wuhan lab because it has a furin cle… https://t.co/yHFJ9Zq75Y Laurie_Garrett (from New York, NY) Fri Dec 17 01:22:47 +0000 2021
We needed leaks to learn about the grant proposal to insert furin cleavage sites into bat coronaviruses. It's extr… https://t.co/g1cIBuuoXX mattwridley (from Northumberland, UK) Thu Dec 16 22:32:35 +0000 2021
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