Wednesday, March 31, 2021

Meet Dr. Sean Kelishadi: “The King of Cleavage” | Seekers Time

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From Publisher: Seekers Time



Not to change the topic here:

Rita Ora teases a hint of cleavage in a plunging yellow silk top in dressing room snaps | Daily

She recently said she 'never' wants to leave Sydney as she fills out her role as a mentor on the latest season of The Voice Australia.

And Rita Ora turned up the heat on Instagram on Thursday as she shared some behind-the-scenes dressing room snaps from a glamorous photoshoot.

The singer, 30, teased a hint of cleavage as she filmed herself modelling a plunging yellow silk top, while a hairdresser styled her locks into Hollywood waves.

The long-sleeved number was adorned with a splatter print design and featured zip detailing which Rita left partially undone.

The RIP songstress accentuated her natural beauty with a bronzed make-up and a slick of pink lipstick.

The star is currently working on the latest series of The Voice in Sydney, after travelling to Australia with her sister Elena, who serves acts as her manager.

During her time off, the blonde beauty has been pictured enjoying the sizzling temperatures in her bikini on Sydney Harbour.

From Publisher: Mail Online



Public's Help Needed to Identify Burglary Suspects, Says HCSO – Redheaded Blackbelt
From Publisher: Redheaded Blackbelt



Demi Lovato showcases her cleavage in a plunging jacket-dress for premiere of YouTube documentary

And on Monday the Sober singer turned more than a few heads when she attended the premiere for the YouTube docuseries at The Beverly Hills Hilton in Beverly Hills.

Lovato, 28, stunned in a plunging white jacket-dress adorned with black ruffles on one of the lapels, part of the collar, and the end of each sleeve.

By going shirtless, the New Mexico native gave more than a hint of her cleavage in the number that fell to about the top of her knees.

Going for a look of yesteryear, Lovato's raven lock glistened under the bright lights and styled in a retro 1920s-30s vibe with a part on the left

With the tuxedo trend continuing to reign supreme, Demi's dress by Martin Martin offers a unique interpretation. Crafted from cream satin, this design is accentuated by contrast buttons and flirty organza ruffles.

Alternatively, champion the craze in a blazer dress from our edit below. With options ranging from PrettyLittleThing to Nasty Gal, every budget is accounted for.

'I had three strokes. I had a heart attack. My doctors said that I had five to 10 more minutes,' Lovato confessed about her opioid overdose at her LA mansion in July 2018, in a clip from the upcoming four-part docuseries.

The team: Lovato also shared the red carpet spotlight with director and executive producer and Scott Ratner at The Beverly Hilton in Beverly Hills

From Publisher: Mail Online



This may worth something:

Billie Eilish Shows Off Major Cleavage On Puppy's First Birthday

Billie Eilish is paying tribute to her bestest friend in the whole world -- her puppy! The "bad guy" singer took to Instagram to shower her furry friend with praise and love one year after she rescued the cute gray pit bull mix. Although she never revealed a name for the pit, the singer clearly made the dog part of the pack, along with her other rescue dogs, Misha and Pepper, and her pet tarantula.

"Happy birthday sweet boy," Billie Eilish captioned a photo of the pup on her Instagram Stories while showing off the last year of fun she has had with the pit bull mix. Eilish first revealed the dog last April during the pandemic when she admitted to having "failed" at fostering the dog as a rescue and just ended up adopting him.

The singer's photos, which included some curvy shots, showed how much her dog has grown over the year, along with how many snuggles he got from the star.

19-year-old Billie Eilish flaunted was seen in a much different look while hanging with her puppy, as she traded in her baggy fashion choices for cozy tops that revealed her ample assets.

It has been a change for the star, as she has opened up in recent months about growing up in the spotlight and learning to love her physical features.

From Publisher: The Blast



Miley Cyrus Flashes Her Cleavage In Snaps Taken By A Famous Friend - The Inquisitr

Miley Cyrus gave Instagram followers a show this weekend, sharing a series of racy snaps that were taken by one of her famous friends.

The pictures, shared on Sunday, showed Miley flashing some cleavage and showing off some rock star attitude. They captured some viral attention, garnering praise from followers and some of Miley's other famous friends. It's the latest racy image that Miley has shared on social media, following up some other even more revealing images that she has posted in recent weeks.

The series of pictures, which can be seen below, showed Miley wearing an all-black outfit, including a top that showed off plenty of skin. In one of the images, she held both sides of her shirt, pulling it slightly open to show off her cleavage as she struck a pose. 

The image showed her sitting on the ground surrounded by tables and chairs, and was taken in black-and-white, giving it an artistic effect. Other pictures taken in the same setting showed Miley flashing a middle finger and putting a mean look on her face.

"Harry, that's easy," she replied. "Justin Bieber I've known way too long, and it's like a family. Harry Styles!"

The revealing snaps of Miley earned some big attention from her followers, racking up more than 1.1 million likes in just a matter of hours. Many of her followers took to the comments section to share some praise for the snaps.

"You are top!!!!" wrote another, ending the comment with a long series of fire emoji. Many others used emoji, using hearts and fire to show their appreciation.

This is not the first time that Miley has shown some skin on social media. She has posted some even racier images on Instagram in recent weeks, including a shot last month that showed her lounging in the bathtub.

As The Inquisitr reported at the time, Miley posed in the nude but used her arm to cover her chest so she remained within Instagram's strict rules against overt nudity. This picture was also a viral hit, racking up many likes and comments.

From Publisher: The Inquisitr



Research identifies ways to prevent coronavirus spread to the nervous system

"Using a common cold coronavirus, similar to SARS-CoV-2, we were able to show that cleavage of the S protein and interferon could prevent its spread to the brain and spinal cord in mice," says Talbot, who has been studying coronaviruses for nearly 40 years.

According to Marc Desforges, currently a clinical specialist in medical biology at the CHU-Sainte-Justine virology laboratory, the cleavage of the S protein by various cellular proteases is essential for these viruses to effectively infect cells and spread to various organs and systems in the body, including the central nervous system (CNS).

Taken together, these results point to two potential antiviral targets: protein S cleavage and effective interferon-related innate immunity.

Understanding the mechanisms of infection and viral propagation in neuronal cells is essential to better design therapeutic approaches. This is especially important for vulnerable populations such as the elderly and immunocompromised.?"

Le Coupanec, A., et al. (2021) Potential differences in cleavage of the S protein and type-1 interferon together control human coronavirus infection, propagation, and neuropathology within the central nervous system. Journal of Virology. doi.org/10.1128/JVI.00140-21 .

From Publisher: News-Medical.net



Study identifies key features in SARS-CoV-2 genome essential for replication in respiratory

Researchers at the Institute of Medical Virology, the University of Zurich in Switzerland, have identified features in the SARS-CoV-2 genome that are important for human respiratory cell growth.

The study, published in the journal PLOS BIOLOGY , uncovered sequence features in SARS-CoV-2 variants that determine cell-specific replication. It underlines the need to monitor SARS-CoV-2 stocks carefully when phenotyping new variants of concern.

Though large-scale sequencing efforts have identified several SARS-CoV-2 variants, it is still unclear whether many of these changes impact viral replication, transmission, and adaptation.

The D614G substitution in the S protein rapidly dominated sequences after it first emerged. This mutation has been tied to increased viral infectivity and replication, facilitating viral spread. Meanwhile, recently acquired mutations in the SARS-CoV-2 genome appear to promote reproduction and transmission in humans.

The researchers described 14 SARS-CoV-2 isolates from patients collected during the first pandemic wave in Switzerland from March to May 2020. These isolates represent several virus clades roaming in Europe in early 2020.

However, rare additional mutations found in the S and E proteins were seen on low-passage virus stock preparation in Vero-CCL81 cells. When the researchers analyzed each SARS-CoV-2 isolate in Vero-CCL81 cells and distinguished primary human bronchial epithelial cells (BEpCs), they found the importance of the S furin cleavage site and E positions 5/6. These determine SARS-CoV-2 infectivity in human respiratory cells.

The researchers also noted that isolates that expressed S G614 appeared to replicate more effectively than isolates with the S D614.

Also, the isolates with Orf3a (Q57H) and nsp2 (T85l) substitutions showed a cell-specific replication phenotype.  Isolates unique in containing these variants replicated less efficiently in Vero-CCL81 cells while maintaining efficient replication capacity in primary human BEpCs.

These variants are found in about 20 percent of SARS-CoV-2 sequences globally. Yet, their functional consequences remain unclear.

From Publisher: News-Medical.net



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